刚下了avastin官网的用药指南:
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Patients should continue treatment until disease progression or unacceptable toxicity.
( r) Q% C' z( \' f" U$ N; v1 Metastatic Colorectal Cancer (mCRC)
2 k4 M. U& h% a B5 _ The recommended doses are 5 mg/kg or 10 mg/kg every 2 weeks when used in combination with
$ m: T1 D3 W( D$ W+ W- B% k, p! vintravenous 5-FU-based chemotherapy.
2 j9 g, C& Q {# h* p• Administer 5 mg/kg when used in combination with bolus-IFL.
7 _: Q4 I; g( _• Administer 10 mg/kg when used in combination with FOLFOX4.
7 {7 b( ]$ m7 ^$ S) G. ~' d2 Non-Squamous Non-Small Cell Lung Cancer (NSCLC) 6 i# H& v0 g5 o$ A; B
The recommended dose is 15 mg/kg every 3 weeks in combination with carboplatin and
. [0 g& l5 B3 C) i3 @, ]paclitaxel. . q. l- O1 a4 s$ U5 `
3 Metastatic Breast Cancer (MBC)
5 U4 M( d, k# ~5 q+ _5 T0 @2 f The recommended dose is 10 mg/kg every 2 weeks in combination with paclitaxel.
& B2 c6 ^ k+ B6 x- ]4 Glioblastoma* u; S/ d; D( Z! X8 S% T8 d
The recommended dose is 10 mg/kg every 2 weeks. ; f( K2 X% o1 R% X9 B9 B$ g0 V
5 Metastatic Renal Cell Carcinoma (mRCC)
1 y( s/ W- M2 n. v' k The recommended dose is 10 mg/kg every 2 weeks in combination with interferon alfa. T# C# X8 ~5 |+ v' v$ f2 s+ E
- X8 z. b2 m- z" j7 Z# M& c" W按照这个说明非小细胞腺癌的服用剂量是15mg/kg,与卡铂紫杉醇合用,avastin每三周用一次。! L0 O# U9 x6 o8 | I" Q8 ?
我妈妈是肺腺癌转肝,体重53kg,现在医生联合卡铂紫杉醇化疗了一个疗程21天。 但avastin不是一次注射的,每7天注射一次200mg,一个疗程21天注射了3次(分别是第一、八、十五天) |