平安！ 发表于 2011-11-9 19:57
6 U5 m$ R$ O$ w+ r4 g2 S1 ~* V. KPazopanib (100 mg/kg/day free base equivalent)
这是个已经在美国上市的老药了，能下载到正式药物使用说明书英文版。3 L# A B/ A' x0 R8 k
搜索了一下，原料一大堆。# a; m& b, C7 h
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对不起！100mg/kg是用于移植瘤的，我弄错了。
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以下是正版说明书的推荐用量。
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--------------------- DOSAGE AND ADMINISTRATION ----------------) S1 g2 I5 V) t7 j! p$ X
* 800 mg orally once daily without food (at least 1 hour before or 2 hours after a meal). (2.1)
& {# n/ n% l: Q- e& G* Baseline moderate hepatic impairment – 200 mg orally once daily. Not recommended in patients with severe hepatic impairment. (2.2)
+ {+ v# A9 w5 X' | K* N v---------------------DOSAGE FORMS AND STRENGTHS --------------2 h7 i" K1 a, P; ~5 b5 Z
200 mg tablets. (3)
1 V% s1 [6 Y7 z z6 l: u-------------------------------CONTRAINDICATIONS------------------------ |
显身卡
